Neutrophil extracellular traps — web-like structures released by immune cells that can promote clotting — are increased during acute episodes and clinical relapses of immune-mediated…
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A mutation in the gene ELF4 likely set the stage for a teenage boy to develop immune thrombocytopenia (ITP), according to a new report. The…
People with von Willebrand disease (VWD) had lower bone mineral density than healthy individuals in a small, single-center study, highlighting the need to consider…
Two teenage brothers in Egypt have been diagnosed with an extremely rare combination of two distinct genetic blood-clotting disorders. The boys carry the genetic mutations…
A 96-year-old woman with inherited type 2A von Willebrand disease and previously mild symptoms experienced a sudden worsening of bleeding after developing acquired von…
Adding Cablivi (caplacizumab-yhdp) to standard treatment for immune-mediated thrombotic thrombocytopenic purpura (iTTP) may help protect the brain by repairing damage to the blood-brain barrier,…
Blocking the activity of an enzyme known as MELK may help boost the production of platelets — tiny cell fragments that improve blood clotting and…
Women with von Willebrand disease (VWD) still experienced a high burden of heavy menstrual bleeding despite commonly using first-line therapies such as tranexamic acid…
People with immune-mediated thrombotic thrombocytopenic purpura (TTP) taking Cablivi (caplacizumab) plus immunosuppressants may need fewer therapeutic plasma exchange sessions than previously thought, a…
Regulatory authorities in Brazil have approved the oral therapy Tavalisse (fostamatinib disodium hexahydrate) for adults with chronic …
