A donor stem cell transplant and follow-up treatments helped a teenage girl achieve long-term remission from refractory immune thrombocytopenia (ITP), according to a case…
News
THROMBOTIC THROMBOCYTOPENIC PURPURA
NewsStudy links immune cell webs to acute iTTP episodes, relapses
Neutrophil extracellular traps — web-like structures released by immune cells that can promote clotting — are increased during acute episodes and clinical relapses of immune-mediated…
IMMUNE THROMBOCYTOPENIA
NewsScientists trace teenage boy’s ITP to mutation in ELF4 gene: Report
A mutation in the gene ELF4 likely set the stage for a teenage boy to develop immune thrombocytopenia (ITP), according to a new report. The…
VON WILLEBRAND DISEASE
NewsNew study finds lower bone density among people with VWD
People with von Willebrand disease (VWD) had lower bone mineral density than healthy individuals in a small, single-center study, highlighting the need to consider…
THROMBOTIC THROMBOCYTOPENIC PURPURA
NewsBrothers found to have rare mix of 2 genetic blood-clotting disorders
Two teenage brothers in Egypt have been diagnosed with an extremely rare combination of two distinct genetic blood-clotting disorders. The boys carry the genetic mutations…
VON WILLEBRAND DISEASE
NewsHeart valve issue exacerbates women’s inherited von Willebrand: Report
A 96-year-old woman with inherited type 2A von Willebrand disease and previously mild symptoms experienced a sudden worsening of bleeding after developing acquired von…
THROMBOTIC THROMBOCYTOPENIC PURPURA
NewsAdd-on Cablivi may may help boost cognitive recovery in iTTP: Study
Adding Cablivi (caplacizumab-yhdp) to standard treatment for immune-mediated thrombotic thrombocytopenic purpura (iTTP) may help protect the brain by repairing damage to the blood-brain barrier,…
IMMUNE THROMBOCYTOPENIA
NewsScientists find new treatment path to improve blood clotting in ITP
Blocking the activity of an enzyme known as MELK may help boost the production of platelets — tiny cell fragments that improve blood clotting and…
VON WILLEBRAND DISEASE
NewsHeavy menstrual bleeding remains burdensome for women with VWD
Women with von Willebrand disease (VWD) still experienced a high burden of heavy menstrual bleeding despite commonly using first-line therapies such as tranexamic acid…
THROMBOTIC THROMBOCYTOPENIC PURPURA
NewsShorter plasma exchange course may be safe with Cablivi in TTP
People with immune-mediated thrombotic thrombocytopenic purpura (TTP) taking Cablivi (caplacizumab) plus immunosuppressants may need fewer therapeutic plasma exchange sessions than previously thought, a…
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