Steroids, IVIG key in successful management of severe immune TTP
Adults with severe immune thrombotic thrombocytopenic purpura (TTP) who are at a high risk of bleeding may be managed in a hospital’s emergency department…
Thrombotic thrombocytopenic purpura
Blood clots in spleen were unusual first sign in case of acquired TTP
A young man with unusual blood clots in the spleen was ultimately diagnosed with immune-mediated thrombotic thrombocytopenic purpura (TTP) — also known as acquired…
COVID-19 in Canada linked to clotting problems but not TTP
The number of cases of the blood disorder thrombotic thrombocytopenic purpura (TTP) did not increase during the pandemic, but COVID-19 was linked to more…
TTP in pregnancy boosts adverse maternal, fetal outcomes: Study
Pregnant women with thrombotic thrombocytopenic purpura (TTP) in the U.S. are nearly 20 times more likely to experience an adverse maternal outcome, according to…
Wayrilz recommended for approval in Europe to treat ITP
An arm of the European Medicines Agency (EMA) is recommending that Wayrilz (rilzabrutinib) be approved to treat adults with immune thrombocytopenia (ITP) who…
Switching to Adzynma slashes hospital stays in congenital TTP
Switching from treatment with fresh frozen plasma (FFP) to Adzynma (ADAMTS13, recombinant-krhn) can help people with congenital thrombotic thrombocytopenic purpura (TTP) avoid hospital stays,…
COVID-19 triggers difficult-to-treat TTP in pregnancy for woman, 41
COVID-19 may trigger or worsen refractory, or difficult-to-treat, thrombotic thrombocytopenic purpura (TTP) during the first months of pregnancy, requiring early diagnosis and aggressive treatment…
Adzynma safely cuts relapse risk in TTP patients, new study finds
The preventive treatment Adzynma (recombinant human ADAMTS13) is safe and effective at reducing disease relapses for people with congenital thrombotic thrombocytopenic purpura (TTP), and…
Combo of blood biomarkers can help predict risk of death in TTP
A combination of blood biomarkers can help predict the short-term risk of death for people admitted to the hospital with thrombotic thrombocytopenic purpura (TTP),…
Anti-ADAMTS13 antibody levels could help guide TTP treatment
Levels of anti-ADAMTS13 antibodies measured after therapeutic plasma exchange (TPE) are associated with the time it takes to achieve normalization of ADAMTS13 activity in people…
