Discussion
The results of a full blood count test — called a CBC, or complete blood count, by clinicians — may help distinguish people with…
Thrombotic thrombocytopenic purpura
Discussion
While standard preventive treatments may reduce the risk of disease flares and organ damage in people with congenital thrombotic thrombocytopenic purpura (TTP), flare-ups can…
Discussion
An Iranian woman with congenital thrombotic thrombocytopenic purpura (TTP) successfully delivered a healthy baby boy after receiving regular infusions of fresh frozen plasma and…
Discussion
Starting plasma exchange — a procedure to replace a portion of a patient’s blood with that of a healthy donor — within one day of…
When a 55-year-old man developed sudden kidney failure, doctors discovered a rare blood-clotting disorder hiding behind a highly unusual genetic profile. A new case report…
Discussion
People in remission from immune-mediated thrombotic thrombocytopenic purpura (iTTP) may have a higher risk of certain major cardiovascular events, particularly stroke, according to a…
Discussion
Four weekly injections of the antibody therapy daratumumab restored a key enzyme’s activity and triggered a two-year recovery for a woman with hard-to-treat immune-mediated…
A 26-year-old woman who arrived at a hospital with lupus and severe thrombocytopenia (very low numbers of blood-clotting platelets) was ultimately diagnosed with immune-mediated…
Discussion
Neutrophil extracellular traps — web-like structures released by immune cells that can promote clotting — are increased during acute episodes and clinical relapses of immune-mediated…
Discussion
Two teenage brothers in Egypt have been diagnosed with an extremely rare combination of two distinct genetic blood-clotting disorders. The boys carry the genetic mutations…
