Following rituximab treatment, people of African ancestry with immune thrombotic thrombocytopenic purpura (iTTP) experience a relapse significantly sooner than individuals with European ancestry, a…
News
IMMUNE THROMBOCYTOPENIA
NewsManaging anxiety levels may improve quality of life for adults with ITP: Study
High levels of anxiety and alexithymia, or difficulty in recognizing and expressing emotions, are associated with significantly poorer quality of life in people with primary…
The many types of von Willebrand disease may be much more common globally than previously thought, a large study of more than 800,000 people…
IMMUNE THROMBOCYTOPENIA
NewsTherapy combo helps 92% of patients with hard-to-treat ITP in trial
A combination of the medicines eltrombopag and cyclosporine A may be effective for controlling immune thrombocytopenia (ITP) that doesn’t respond well to initial treatment…
VON WILLEBRAND DISEASE
NewsNew gene-editing therapy targets shared genetic markers to treat VWD
Scientists have developed a gene-editing therapy to selectively disable the genetic mutations responsible for Von Willebrand disease (VWD) type 2, regardless of subtype, potentially…
THROMBOTIC THROMBOCYTOPENIC PURPURA
NewsChanges in enzyme shape may help predict iTTP relapse risk
The shape of the ADAMTS13 enzyme during remission (a period when symptoms ease or disappear) may help predict which people with immune-mediated thrombotic thrombocytopenic…
IMMUNE THROMBOCYTOPENIA
NewsAltered fat metabolism may help identify ITP patients: Study
Lipid, or fat, metabolism is altered in people with immune thrombocytopenia (ITP), resulting in distinct metabolic signatures that could help distinguish ITP patients from healthy…
VON WILLEBRAND DISEASE
NewsCareful planning guides surgery in patients with rare bleeding disorders
A recent case report highlights the challenges of performing surgery in a patient with more than one bleeding disorder. Two doctors in Portugal described their…
THROMBOTIC THROMBOCYTOPENIC PURPURA
NewsSilent brain damage in iTTP tied to age, diabetes, and heart disease: Study
More than half of individuals who recover from an acute episode of immune-mediated thrombotic thrombocytopenic purpura (iTTP) may have silent brain damage — where…
IMMUNE THROMBOCYTOPENIA
NewsScientists say blood test can predict treatment effectiveness in ITP
The size of platelets, the cell fragments that help blood clot, and the levels of certain immune cells in the body may help predict the…
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- Off-label therapy helps control severe bleeding in acquired VWS case
